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ESMO 2024 preview – Astellas unveils its KRAS degrader

ASP3082 grabs some early attention among degraders set to feature at ESMO.

ESMO 2024 preview – conjugates in the spotlight

Early attention falls on ADCs originated by ProfoundBio, SystImmune, MediLink and Seagen.

ESMO 2024 preview – Summit and BioNTech battle again

The companies’ PD-(L)1 x VEGF bispecifics will clash in triple-negative breast cancer.

Novartis drops out of KRAS

While Roche, Lilly and Merck push on aggressively, Novartis throws in the towel.

No shortcuts for Agenus

The FDA throws out the company’s second attempt at an accelerated approval.

A second-line degrader battle beckons

Readouts for Lilly and Pfizer/Arvinas loom, but many SERD hopefuls are now focused on earlier-stage breast cancer.