ESMO 2024 – Astellas defends its degrader
Despite seeing dose-limiting toxicities, the group is going higher with its KRAS G12D project.
Despite seeing dose-limiting toxicities, the group is going higher with its KRAS G12D project.
The companies hopes to be as efficacious as ex vivo therapy, with convenience and safety advantages.
Data in the coming months will inform which immunotherapy the UK company takes into pivotal development.
The group plays down upcoming interim analysis, but still hopes for accelerated approval.
The group’s Kelun-partnered TROP2 ADC looks like a bargain, but Merck’s pipeline has big shoes to fill.
The company defends its cancer strategy, and says it's not a me-too developer.
The group is keeping faith with the novel target KLK2.
SEZ6 looks promising but early, while questions remain around toxicity with AbbVie's cMet ADCs.
Amid doubts about early data with FG-3246, the group is scathing about its rivals.
More efficient internalisation and release – not bystander activity – are the focus for this private ADC player.