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Warning signs for Xencor

Data on the group’s lead project, the PD-1 x CTLA-4 bispecific vudalimab, are far from emphatic.

Astra takes Steap2 into human trials

First-in-human clinical trial listings include AZD0754, Astra’s internally developed Car-T therapy.

Revolution pushes home its pan-KRAS advantage

Not long after starting phase 1, RMC-6236 could be in pivotal trials this year.

Janux gives conditionally acting therapeutics hope

Early activity of JANX007 in prostate cancer sees Janux stock gain 190%.

Safety remains in focus for Cogent’s bezuclastinib

An “optimised formulation” of bezuclastinib looks promising, but the safety question remains open.

Arcus makes its HIF2α pitch

After living in the shadow of Arcus’s TIGIT project, casdatifan might soon come into its own.

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