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FDA green and red lights: April 2024

A tumour-agnostic label for Enhertu leads April’s US oncology approvals.

CytomX delivers a pancreatic surprise

But the group’s attempt to join Janux at the high altar of masking technology falls flat.

Calliditas puts a brave face on setanaxib failure

A phase 2 head and neck trial missed its primary endpoint, but the group is taking heart from survival data.

Glycomimetics down and out on upro miss

The company’s long-delayed pivotal trial is hit by a stronger-than-expected placebo performance.

A new menin challenger

Hutchmed starts phase 1 with a project in a field where Syndax and Kura have so far been the main players.

BridgeBio’s oncology spinout must stand out from the crowd

The new developer will focus on the crowded KRAS space and PI3Kα/AKT inhibition, which has been hit by toxicity issues.