Imbruvica faces challenges on multiple fronts.

Competitors struggle, while MorphoSys investors see a path forward for pelabresib after all.

Dizal got a lucky break with golidocitinib, and now mid-stage data back the project’s activity in T-cell lymphoma.

Blueprint looks to a next-gen Ayvakit, while Cogent challenges with a molecule acquired from Daiichi Sankyo.

Arvinas’s SERD appears to edge out Olema’s, but what’s the best CDK4/6 inhibitor for a phase 3 combination?

With inavolisib’s pivotal front-line win Roche reckons it can knock out Novartis’s Piqray.

Jaypirca secures a CLL label, though plans to dominate will be tempered by this market’s fast-changing nature.

Novartis' Jakafi faces competition from GSK's momelotinib, while Astra looks over its shoulder at Merck in biliary tract cancer.