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ESMO 2025 – domvanalimab flies the flag for TIGIT

Full data from Edge-Gastric are presented at ESMO.

ESMO 2025 – Tubulis keeps the NaPi2b dream alive

The first TUB-040 data come just after Tubulis raised €308m.

ESMO 2025 – Lilly overshadows Astra’s folate reveal

The battle intensifies as LY4170156 matches torvuta-S with activity in FRα <25% expresers.

ESMO 2025 – Novartis looks for Pluvicto prostate Addition

But the ESMO discussant recommends against widespread use in hormone-sensitive disease.

ESMO 2025 – Padcev plus Keytruda sets the perioperative bar

Keynote-905 finds a 50% reduction in the risk of death in (neo)adjuvant muscle-invasive bladder cancer.

ESMO 2025 – Roche sticks it to its SERD rivals

But it will be up to regulators to decide if giredestrant has done enough for an all-comers label.