Response rates in relapsed NPM1-mutant AML look slightly worse than before, but QTc prolongation could be the real worry.
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AbbVie looks to justify its faith in TeneoOne, and Bristol its phase 3 move with BMS-986393.
Prelude’s SMARCA2 project and C4’s BRAF hopeful look lacklustre.
Backed by a slender survival signal the industry’s only anti-fucosyl-GM1 MAb is to go pivotal.
So far ASP3082 looks no better than Jiangsu HengRui’s straight KRAS G12D inhibitor.
The small cap biotech Instil Bio tries to follow in Summit’s slipstream.
Early data suggest that PD-(L)1 x VEGF bispecifics might challenge Keytruda in triple-negative disease.
Data suggest a path forward for olomorasib plus Keytruda and chemo in PD-L1 low and negative patients.
