Targeted lung cancer niche sees a German pharma battle
But could toxicity be holding back filing plans?
But could toxicity be holding back filing plans?
The group goes after a KRAS-related target on which Boehringer recently gave up.
Spectrum’s poziotinib failed in HER2 exon 20 lung cancer, but that isn’t stopping Boehringer and Bayer.
As BAY2927088 enters phase 3 its lung cancer use will no longer be limited to exon 20.
Blockade of CCR8 has quietly emerged as a hot oncology target, especially for anti-PD-(L)1 MAb combinations.
The company reckons its tech could solve problems with current ADCs, but the market isn’t giving it much credit yet.
First-in-human trial initiations feature anti-PSMA radioligands, KRAS G12D, Nectin-4 and more.
Analysis of industry assets newly into human trials reveals three Car-T therapies and some familiar targets.