ASCO-GI – Leap falters again
Randomised data will be needed to answer lingering questions about DKN-01.
Randomised data will be needed to answer lingering questions about DKN-01.
Opdivo plus Yervoy scores a remarkable survival benefit in Checkmate-8HW, whose control arm presents some comparability difficulties.
The German group hopes to expand its colorectal cancer offering, taking on the only SLC6A8 inhibitor in development.
The latest failure, in colorectal cancer, follows a recent disappointment in second-line liver.
As a key mid-stage readout approaches for the group’s neoantigen immunotherapy, Gritstone still has much to prove.
And first data with a low dose are particularly unimpressive.