ESMO 2025 – Enhertu’s perioperative Destiny beckons
Enhertu improves outcomes in (neo)adjuvant breast cancer, but toxicity resurfaces.
Enhertu improves outcomes in (neo)adjuvant breast cancer, but toxicity resurfaces.
Boehringer’s Hernexeos and Bayer’s sevabertinib look similar in first-line HER2-mutant NSCLC.
And Vironexis’s second gene therapy-encoded T-cell engager will soon go clinical.
A phase 3 trial of Hernexeos in adjuvant HER2m NSCLC is planned.
The ESMO presidential session will feature data from Destiny-Breast05 and 11.
Meanwhile, Astra, Merck and Novartis look for new Enhertu, Keytruda and Pluvicto additions.
The company, apparently unbothered by Enhertu, is starting a new HER2 x HER2 phase 3.