ESMO 2023 – GSK sets up Pfizer battle in B7-H4
Early data on Hansoh’s HS-20089 were enough to tempt GSK, but Seagen isn't far behind.
Early data on Hansoh’s HS-20089 were enough to tempt GSK, but Seagen isn't far behind.
In paying $5.5bn for immediate rights to three Daiichi Sankyo assets Merck & Co has made its biggest bet on ADCs to date.
However, lack of meaningful efficacy in Tropion-Lung01 suggests that datopotamab deruxtecan might be restricted to a histology-defined NSCLC subgroup.
A study to back accelerated approval is to start next year, but the prospect of seeing a fully greenlit Padcev before then looms large.
One first-in-human study and two deals in a single day sees companies blaze the ADC trail.
Seagen/Genmab’s confirmatory cervical cancer trial is toplined positive, putting up a fresh roadblock for Iovance’s accelerated filing plans.