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  1. J&J deal cements Ambrx’s transformation

    … cohorts 4-8 the confirmed ORR was 22%.   Source: ESMO 2023.   Any lingering doubts now become …

    - 01/10/2024 - 14:31

  2. Merck’s latest move is in bispecifics

    … toxicity.  In a phase 1/2 study presented at ESMO 2023 HPN328 produced a confirmed response rate of 32% … house Ph1 +/- Keytruda in solid tumours ; data at ESMO 2023 Not yet given Source: Mizuho note, …

    - 06/19/2024 - 16:48

  3. ASCO-GI preview: notable late-breakers

    … 604 KRAS G12C inhibitor with solid tumour data at ESMO 2023 Defiance Leap Therapeutics DKN-01 + …

    - 01/09/2024 - 11:43

  4. Merck KGaA takes a punt on Inspirna’s novel approach

    … with ompenaclid in second-line CRC Source: ESMO 2023.   By way of benchmarks, Folfiri chemo …

    - 01/05/2024 - 13:36

  5. Bristol makes its radiopharma move

    … data are expected late 2025 or early 2026 . At ESMO 2023, phase 1b data from that study found a 29% overall …

    - 01/03/2024 - 17:27

  6. More warnings signs for ATR inhibition

    … ph1/2 +/- gemcitabine/irinotecan in solid tumours at ESMO 2023 IMP9064 Impact Therapeutics First data from ph1/2 +/- senaparib in solid tumours at ESMO 2023 Camonsertib Roche (licensed from Repare) …

    - 11/14/2023 - 10:58

  7. ESMO 2023 movers – who won and who lost?

    ESMO 2023 movers – who won and who lost? …

    - 12/14/2023 - 11:53

  8. ESMO 2023 – BioNTech still has work to do on Claudin6

    ESMO 2023 – BioNTech still has work to do on Claudin6 … trial +/- CARVac in CLDN6+ solid tumours (NCT04503278) ESMO 2023 with automated manufacturing: 45% ORR (17/38) …

    - 07/10/2024 - 10:07

  9. ESMO 2023 – Nectin-4 in focus

    ESMO 2023 – Nectin-4 in focus Quick …

    - 10/24/2023 - 14:58

  10. ESMO 2023 – how datopotamab's lung side effects are graded

    ESMO 2023 – how datopotamab's lung side effects are graded …

    - 10/24/2023 - 14:57