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  1. ELCC 2025 – BioNTech impresses in small-cell lung

    … 42% – lower than the 73% reported from the same study at ESMO 2023. Still, the result is in line with the 40% ORR …

    - 03/28/2025 - 15:08

  2. AACR 2025 preview – distressed biotechs seek redemption

    … Ph1 low-dose irinotecan combo Had monoRx data at ESMO 2023 D3S-001 KRAS G12C inhibitor D3 Bio …

    - 03/28/2025 - 08:55

  3. Imfinzi puts its flag on the Matterhorn

    … already read out positively for pCR, with data presented at ESMO 2023, but the trial remained blinded for EFS, and it's … PD-L1 at a level of at least 1%. It will be noted that ESMO 2023 showed Matterhorn's pCR benefit to be strongest in …

    - 03/11/2025 - 15:11

  4. Bristol exits KRAS G12D

    … Hengrui) Inhibitor Lacklustre ph1 data at ESMO 2023 GFH375 Verastem/GenFleet Inhibitor …

    - 03/06/2025 - 13:30

  5. ASCO-GU – Pfizer looks for bigger bladder cancer invasion

    … urothelial cancer + Keytruda, vs chemo Data at ESMO 2023: 53% reduction in risk of death; FDA approved Dec …

    - 02/12/2025 - 15:51

  6. Two more reasons for GSK to be wary of Tim-3

    … as sabestomig had posted mediocre efficacy data at ESMO 2023 . Its discontinuation means that GSK's cobolimab …

    - 02/06/2025 - 15:35

  7. AstraZeneca doubles down on GPC3

    … which had yielded phase 1 safety and biomarker data at ESMO 2023. The company didn’t give a reason for its …

    - 02/05/2025 - 14:05

  8. Mersana shows that B7-H4 expression matters

    … basis of a 29% ORR among 28 TNBC patients, reported at ESMO 2023 . However, while this Chinese trial enrolled …

    - 02/05/2025 - 10:14

  9. Triple meeting 2024 – Zai Lab impresses in small cell

    … Presentation venue Triple meeting 2024 ESMO 2023 ASCO 2024 ORR 74% (14/19)* 40% …

    - 10/29/2024 - 13:27

  10. Merck and Daiichi look beyond small cell with ifinatamab

    … Safety, antitumour activity Data at WCLC & ESMO 2023: ORR 52% in SCLC; 21% in ESCC; 25% in mCRPC; 31% …

    - 10/24/2024 - 13:51