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Venture-backed biotechs push into the clinic

The latest first-in-human study initiations will be of interest to followers of D2M Therapeutics, Nested and Volastra.

Nuvation takes the battle to Nuvalent

The takeover of AnHeart centres on advancing the latter’s targeted lung cancer project taletrectinib.

FDA knocks back Regeneron’s CD20 T-cell engager

The decision highlights the fact that Regeneron is still doing dose-finding work for odronextamab.

J&J speeds into new bladder cancer trial

The company takes another project from Taris into phase 3 as it chases a $5bn market.

Ascentage’s Venclexta challenge looks wildly optimistic

A just revealed clinical trial listing shows Ascentage’s BCL-2 inhibitor being compared against an outdated standard of care.

Immutep approaches Lag3 crunch time

Results with eftilagimod alpha in first-line head and neck cancer threaten to cloud partnering prospects.

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