A pipeline update reveals the dropping of RC248, after cMet and Claudin18.2 ADCs disappeared earlier.
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The first global phase 3 trial will be in first-line triple-negative breast cancer.
Tropion-Lung10 will combine dato-dxd with rilvegostomig, and focus on PD-L1 and TROP2 expression.
Two pancreatic cancer trials will read out this quarter, but after a string of failures with the project they look like a long shot.
Early data with the group’s personalised project intrigue, but Transgene has a long road ahead.
One of the first human datasets concerning an ATM inhibitor shows glioblastoma’s intractability.
First-in-human study initiations feature variations on well-trodden targets, plus a minor hiccup for OncoC4.
After numerous IL-2 failures there are glimmers of hope for the group’s contender, MDNA11.