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US shutdown freezes new drug applications

Key FDA decisions are expected to face delays.

Astra's clash of the T-cell engager Titans

The Titan CD8-guiding technology seems to have spawned a new variant.

Takeda’s cancer prospects dim further

After trimming its cell therapy pipeline last year, the group is now out entirely.

Zelgen’s DLL3 trispecific goes pivotal

A Chinese phase 3 of the biparatopic DLL3 T-cell engager alveltamig will start soon.

ESMO 2025 preview – Merck hopes for Daiichi redemption

The first pivotal data with raludotatug deruxtecan will feature as a late-breaker.

FDA red and green lights: September 2025

A single-arm trial was enough for J&J’s Inlexzo nod.